Plant sterols and stanols: Their role in health and disease
نویسندگان
چکیده
منابع مشابه
The role of dietary supplementation with plant sterols and stanols in the prevention of cardiovascular disease.
Several studies have shown that increased levels of low-density lipoprotein (LDL) cholesterol predict cardiovascular events. The Adult Treatment Panel II (ATP II) introduced the principle of therapeutic lifestyle changes, including plant sterols/stanols for the management of LDL cholesterol. Plant sterols and stanols in fat matrices effectively lower LDL cholesterol levels in hypercholesterolem...
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15 صفحه اولCholesterol-lowering Sterols and Stanols
Unfortunately, whilst the in vitro evidence for their beneficial effects on lipid profile is convincing, this does not translate with any compelling degree into prevention of primary cardiovascular events. Except in borderline normo/hypercholesterolaemia, prescription drugs (eg, statins) are more effective than stanol/sterol esters for lowering LDL cholesterol. The National Institute for Health...
متن کاملComparison of the intestinal uptake of cholesterol, plant sterols, and stanols in mice.
The recent identification of the aberrant transport proteins ABCG5 and ABCG8 resulting in sitosterolemia suggests that intestinal uptake of cholesterol is an unselective process, and that discrimination between cholesterol and plant sterols takes place at the level of sterol efflux from the enterocyte. Although plant sterols are structurally very similar to cholesterol, differing only in their ...
متن کاملEfficacy and safety of plant stanols and sterols in the management of blood cholesterol levels.
Foods with plant stanol or sterol esters lower serum cholesterol levels. We summarize the deliberations of 32 experts on the efficacy and safety of sterols and stanols. A meta-analysis of 41 trials showed that intake of 2 g/d of stanols or sterols reduced low-density lipoprotein (LDL) by 10%; higher intakes added little. Efficacy is similar for sterols and stanols, but the food form may substan...
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ژورنال
عنوان ژورنال: Journal of Clinical Lipidology
سال: 2008
ISSN: 1933-2874
DOI: 10.1016/j.jacl.2008.01.007